Clinical Associations of Deliberate Self-Injury and Its Impact on the Outcome of Community-Based and Long-Term Inpatient Treatment for Personality Disorder

Background: Deliberate self-injury (DSI) is significantly associated with personality disorder (PD). There are gaps in our knowledge of DSI as an indicator of severity of psychopathology, as moderator of outcome and with regard to its response to different treatment programs and settings. Methods: We compare 2 samples of PD with (n = 59) and without (n = 64) DSI in terms of clinical presentation, response to psychosocial treatment and relative outcome when treated with specialist long-term residential and community-based programs. We test the assumption that DSI is an appropriate indicator for long-term inpatient care by contrasting the outcomes (symptom severity and DSI recidivism) of the 2 DSI sub-groups treated in the 2 different approaches. Results: PD with DSI had greater severity of presentation on a number of variables (early maternal separation, sexual abuse, axis-I comorbidities, suicidality and inpatient episodes) than PD without DSI. With regard to treatment response, we found a significant 3-way interaction between DSI, treatment model and outcome at 24-month follow-up. PD with DSI treated in a community-based program have significantly greater chances of improving on symptom severity and recidivism of self-injurious behaviour compared to PD with DSI treated in a long-term residential program. Conclusions: Although limitations in the study design invite caution in interpreting the results, the poor outcome of the inpatient DSI group suggests that explicit protocols for the management of DSI in inpatient settings may be beneficial and that the clinical indications for long-term inpatient treatment for severe and non-severe PD may require updating. Copyright (C) 2010 S. Karger AG, Base

Electroweak corrections in the Sudakov limit at the LHC

At hadron colliders the production of a Z boson in association with jets represents an irreducible Standard Model background to direct searches for New Physics based on the signatures with several jets and missing transverse momentum. Using the algorithm developed by Denner and Pozzorini recently implemented in the ALPGEN event generator, one loop virtual weak corrections to Z+2 and Z+3 jets in the Sudakov limit have been computed. For the standard event selection considered by the ATLAS and CMS Collaborations, these corrections can grow up to −40, −45% at √s = 14Tev and become even larger at future proton-proton colliders where the higher energies will allow to study more and more extreme kinematical regions. Finally, also the effect of real weak corrections to the processes to Z + 2 and Z + 3 jets is briefly discussed

Electromechanical Quantum Simulators

Digital quantum simulators are among the most appealing applications of a quantum computer. Here we propose a universal, scalable, and integrated quantum computing platform based on tunable nonlinear electromechanical nano-oscillators. It is shown that very high operational fidelities for single and two qubits gates can be achieved in a minimal architecture, where qubits are encoded in the anharmonic vibrational modes of mechanical nanoresonators, whose effective coupling is mediated by virtual fluctuations of an intermediate superconducting artificial atom. An effective scheme to induce large single-phonon nonlinearities in nano-electromechanical devices is explicitly discussed, thus opening the route to experimental investigation in this direction. Finally, we explicitly show the very high fidelities that can be reached for the digital quantum simulation of model Hamiltonians, by using realistic experimental parameters in state-of-the art devices, and considering the transverse field Ising model as a paradigmatic example.Comment: 14 pages, 8 figure

The Importance of Suspension Stability for the Hot-wire Measurements of Thermal Conductivity of Colloidal Suspensions.

The development of advanced heat transfer fluids with enhanced thermal conductivity is essential to improve the effective heat transfer behavior of conventional coolants. Thermal conductivity enhancement has been reported for colloidal suspensions formulated with different nanoparticles. Reliable thermal conductivity measurement requires that the suspension is stable against sedimentation during the measurement since particle sedimentation may effect the experimental results. The present study proposes a criterion to ensure that thermal conductivity data is independent of the particle sedimentation. A measuring device based on the transient hot-wire method is designed to allow vertical and horizontal thermal conductivity data collection. Our investigation shows that the thermal conductivity measurements in the horizontal and vertical configurations are almost identical when the colloidal suspension is stable while they differ for unstable systems

The Finite Size Error in Many-body Simulations with long-Ranged Interactions

We discuss the origin of the finite size error of the energy in many-body simulation of systems of charged particles and we propose a correction based on the random phase approximation at long wave lengths. The correction comes from contributions mainly determined by the organized collective oscillations of the interacting system. Finite size corrections, both on kinetic and potential energy, can be calculated within a single simulation. Results are presented for the electron gas and silicon.Comment: 4 pages, 4 figures, submitted to PRL; corrected typo

Quantum Monte Carlo estimators for the positron-electron annihilation rate in bound and low-energy scattering states

Variational and exact estimators for the positron-electron annihilation rate in bound states of systems containing a positron in the framework of quantum Monte Carlo methods are presented. The modification needed to compute the effective number of electrons Z(eff) when scattering states are concerned is also discussed. The algorithms are tested against four cases for which close to exact results are available, finding an overall good agreement. The systems are Ps(-), PsH, and the s-wave scattering component of e(+)H and e(+)He